Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 4/20 | 0.32 |
| ▸ | ACHE | P22303 | 4/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979164 | 0.90 | MAPT (0.34) | MAPTSTAT3KMT2ABCHEACHE | |
| SCHEMBL23576649 | 0.90 | MAPT (0.34) | MAPTSTAT3KMT2ABCHEACHE | |
| SCHEMBL23601260 | 0.88 | MAPT (0.38) | MAPTSTAT3KMT2ASMN1; SMN2POLB | |
| SCHEMBL23601726 | 0.87 | MAPT (0.40) | MAPTSTAT3KMT2ASMN1; SMN2POLB | |
| SCHEMBL23601778 | 0.84 | MAPT (0.39) | MAPTSTAT3KMT2ASMN1; SMN2POLB | |
| SCHEMBL23601313 | 0.84 | PTAFR (0.33) | BCHEACHEGRIN1GRIN2APOLB | |
| SCHEMBL23601409 | 0.84 | PER2 (0.30) | — | |
| SCHEMBL23577967 | 0.84 | MAPT (0.31) | MAPT | |
| SCHEMBL23576973 | 0.84 | PER2 (0.32) | — | |
| SCHEMBL23601486 | 0.84 | PER2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |