Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601343 | 0.89 | KMT2A (0.36) | HPGDHSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL23601479 | 0.85 | KMT2A (0.46) | HPGDHSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL23601296 | 0.84 | KDM4E (0.34) | HPGDHSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL31229468 | 0.84 | KDM4E (0.34) | HPGDHSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL23577430 | 0.84 | KDM4E (0.34) | HPGDHSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL23601018 | 0.80 | MAPT (0.38) | HPGDHSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL23576906 | 0.79 | MAPT (0.42) | HPGDHSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL31229687 | 0.79 | MAPT (0.42) | HPGDHSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL23601076 | 0.78 | MAPT (0.39) | HPGDHSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL23601746 | 0.76 | MAPT (0.38) | HPGDHSD17B10KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |