Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601478 | 0.90 | MAPT (0.42) | MAPTKMT2ASTAT3KDM4EPOLB | |
| SCHEMBL30047664 | 0.90 | MAPT (0.43) | MAPTKMT2ASTAT3KDM4EPOLB | |
| SCHEMBL23601080 | 0.89 | MAPT (0.39) | MAPTKMT2ASTAT3KDM4EPOLB | |
| SCHEMBL23601474 | 0.87 | MAPT (0.41) | MAPTKMT2ASTAT3KDM4EPOLB | |
| SCHEMBL23601021 | 0.84 | MAPT (0.44) | MAPTKMT2ASTAT3KDM4EPOLB | |
| SCHEMBL23601999 | 0.84 | MAPT (0.37) | MAPTKMT2ASTAT3KDM4EHPGD | |
| SCHEMBL31229669 | 0.83 | MAPT (0.37) | MAPTKMT2ASTAT3KDM4ESMN1; SMN2 | |
| SCHEMBL23601726 | 0.83 | MAPT (0.40) | MAPTKMT2ASTAT3KDM4EPOLB | |
| SCHEMBL23601082 | 0.82 | MAPT (0.39) | MAPTKMT2ASTAT3KDM4ERXRA | |
| SCHEMBL23601083 | 0.82 | MAPT (0.39) | MAPTKMT2ASTAT3KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |