Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909137 | 0.90 | MAPT (0.39) | MAPTPOLBKMT2ASTAT3KDM4E | |
| SCHEMBL23577020 | 0.90 | MAPT (0.39) | MAPTPOLBKMT2ASTAT3KDM4E | |
| SCHEMBL23601035 | 0.89 | MAPT (0.43) | MAPTPOLBKMT2ASTAT3KDM4E | |
| SCHEMBL23601478 | 0.85 | MAPT (0.42) | MAPTPOLBKMT2ASTAT3KDM4E | |
| SCHEMBL23601726 | 0.84 | MAPT (0.40) | MAPTPOLBKMT2ASTAT3KDM4E | |
| SCHEMBL23601079 | 0.83 | KDM4E (0.34) | MAPTKDM4ERXRARXRBRXRG | |
| SCHEMBL23601474 | 0.83 | MAPT (0.41) | MAPTPOLBKMT2ASTAT3KDM4E | |
| SCHEMBL23601083 | 0.82 | MAPT (0.39) | MAPTPOLBKMT2ASTAT3KDM4E | |
| SCHEMBL23601778 | 0.82 | MAPT (0.39) | MAPTPOLBKMT2ASTAT3KDM4E | |
| SCHEMBL29909054 | 0.81 | MAPT (0.33) | MAPTKMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |