SCHEMBL23601121

SCHEMBL23601121

O=C(O)c1c(F)c(F)c(F)c(F)c1S

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.36
KMT2A Q03164 7/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
GAA P10253 1/20 0.34
HTT P42858 2/20 0.33
PKM P14618 1/20 0.33
MAPK1 P28482 2/20 0.33
TSHR P16473 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ASPH Q12797 1/20 0.30
KDM8 Q8N371 1/20 0.30
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10613610 0.92 MEN1 (0.35) MEN1KMT2ASMN1; SMN2CRHBPCRHR2
SCHEMBL25396101 0.89 CYP1A2 (0.33) MEN1KMT2ASMN1; SMN2CRHBPCRHR2
SCHEMBL2356152 0.86 MEN1 (0.33) MEN1KMT2ASMN1; SMN2CRHBPCRHR2
SCHEMBL10613401 0.84 MEN1 (0.32) MEN1KMT2ASMN1; SMN2CRHBPCRHR2
SCHEMBL23601099 0.81 MEN1 (0.40) MEN1KMT2ASMN1; SMN2CRHBPCRHR2
SCHEMBL29449985 0.80 CES2 (0.43) MEN1KMT2ASMN1; SMN2CRHBPCRHR2
SCHEMBL336394 0.80 CES2 (0.43) MEN1KMT2ASMN1; SMN2CRHBPCRHR2
SCHEMBL203915 0.80 CES2 (0.43) MEN1KMT2ASMN1; SMN2CRHBPCRHR2
SCHEMBL10454093 0.77 CES2 (0.42) MEN1KMT2ASMN1; SMN2CRHBPCRHR2
Fluoride SCHEMBL6448131 0.77 CES2 (0.42) MEN1KMT2ASMN1; SMN2CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021131845-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD FOR FORMING PATTERN JSR株式会社 2021-07-01 WO disclosed