SCHEMBL23601233

SCHEMBL23601233

Cc1ccc2c(N(C)c3cc(F)cc(C#CC4(C(F)(F)F)CC4)c3)nc3nncn3c2c1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PARP15 Q460N3 1/20 0.31
PARP10 Q53GL7 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
PARP2 Q9UGN5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576803 0.92
SCHEMBL29909125 0.92
SCHEMBL24721440 0.92 MAT2A (0.31)
SCHEMBL23576747 0.91
SCHEMBL29909760 0.91
SCHEMBL31169395 0.89
SCHEMBL23578119 0.89
SCHEMBL23601527 0.85
SCHEMBL31169407 0.85
SCHEMBL23576840 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 WO disclosed