Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15525319 | 0.87 | MAPT (0.44) | ABL1TP53MDM2GAAALDH1A1 | |
| SCHEMBL3274931 | 0.82 | KDM4E (0.43) | ABL1GAAALDH1A1KDM4EMAPT | |
| SCHEMBL3856555 | 0.82 | ABL1 (0.54) | ABL1TP53MDM2GAAALDH1A1 | |
| SCHEMBL20644102 | 0.82 | ACLY (0.46) | ABL1GAAALDH1A1MAPTHPGD | |
| SCHEMBL25747027 | 0.81 | CYP3A4 (0.47) | ABL1GAAALDH1A1KDM4EMAPT | |
| SCHEMBL8574438 | 0.81 | ABL1 (0.53) | ABL1TP53MDM2GAAALDH1A1 | |
| SCHEMBL30699260 | 0.80 | CYP3A4 (0.40) | ABL1GAAALDH1A1KDM4EMAPT | |
| SCHEMBL25009152 | 0.80 | CYP3A4 (0.40) | ABL1GAAALDH1A1KDM4EMAPT | |
| SCHEMBL28129922 | 0.80 | CFTR (0.50) | ABL1TP53MDM2GAAALDH1A1 | |
| SCHEMBL16637069 | 0.79 | NOTUM (0.41) | ABL1GAAALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |