Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601036 | 0.97 | MAPT (0.35) | MAPTKDM4ERXRARXRBRXRG | |
| SCHEMBL24814655 | 0.92 | MAPT (0.34) | MAPTKDM4E | |
| SCHEMBL30047514 | 0.89 | MAPT (0.34) | MAPTKDM4E | |
| SCHEMBL23601082 | 0.87 | MAPT (0.39) | MAPTKDM4ERXRARXRBRXRG | |
| SCHEMBL23578204 | 0.85 | MAPT (0.31) | MAPT | |
| SCHEMBL23601575 | 0.85 | — | — | |
| SCHEMBL24814660 | 0.85 | — | — | |
| SCHEMBL23601017 | 0.85 | MAPT (0.34) | MAPTKDM4E | |
| SCHEMBL24813523 | 0.84 | — | — | |
| SCHEMBL23601474 | 0.83 | MAPT (0.41) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |