SCHEMBL23601017

SCHEMBL23601017

Cc1cccc2c1OCCCN2c1nc2nnc(C)n2c2ccc(F)c(F)c12

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.34
PIK3CD O00329 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23601506 0.90 MAPT (0.37) MAPTPIK3CDKDM4E
SCHEMBL23577930 0.85 MAPT (0.30) MAPT
SCHEMBL23601708 0.85 HTR1A (0.31) MAPT
SCHEMBL23601036 0.85 MAPT (0.35) MAPTKDM4E
SCHEMBL23601462 0.85 MAPT (0.35) MAPTKDM4E
SCHEMBL23601263 0.84 HTR1A (0.30)
SCHEMBL24721261 0.84 MAPT (0.31) MAPT
SCHEMBL23601018 0.84 MAPT (0.38) MAPTPIK3CDKDM4E
SCHEMBL24813163 0.84
SCHEMBL30047844 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 WO disclosed