Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435339 | 0.79 | GRIN2D (0.55) | CYP2C9ALDH1A1PKMHPGDGRIN2D | |
| SCHEMBL598140 | 0.78 | ALDH1A1 (0.52) | CYP2C9ALDH1A1TSHRGAAUSP2 | |
| SCHEMBL1611358 | 0.77 | CYP2C9 (0.46) | CYP2C9ALDH1A1TSHRGAAUSP2 | |
| SCHEMBL1611732 | 0.77 | CYP2C9 (0.46) | CYP2C9ALDH1A1TSHRGAAUSP2 | |
| SCHEMBL12402558 | 0.77 | ALDH1A1 (0.51) | CYP2C9ALDH1A1TSHRGAAPKM | |
| SCHEMBL1532117 | 0.75 | TYR (0.61) | CYP2C9ALDH1A1TSHRGAAUSP2 | |
| SCHEMBL716407 | 0.75 | ALDH1A1 (0.48) | CYP2C9ALDH1A1TSHRGAAUSP2 | |
| SCHEMBL11517329 | 0.75 | ALDH1A1 (0.48) | CYP2C9ALDH1A1TSHRGAAUSP2 | |
| SCHEMBL18433031 | 0.75 | GRIN2D (0.43) | ALDH1A1HPGDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL22389454 | 0.75 | SMN1; SMN2 (0.48) | ALDH1A1GAAALOX15HSD17B10GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130454-A1 | DENDRIMERS HAVING THIOPHOSPHORAMIDATE PATTERNS AND DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) | 2021-07-01 | — | — | WO | disclosed |