Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23573047 | 0.88 | POLB (0.53) | POLBAPEX1HTTTDP1MAPT | |
| Formaldehyde SCHEMBL28047211 | 0.85 | POLB (0.48) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL17472504 | 0.85 | HTT (0.50) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL23601570 | 0.83 | ADRB2 (0.41) | POLBAPEX1HTTTDP1ADRB2 | |
| SCHEMBL23601631 | 0.83 | MAP2K1 (0.37) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL23601634 | 0.81 | TSHR (0.36) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL12036420 | 0.77 | HTT (0.47) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL23601571 | 0.77 | ADRB2 (0.33) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL3680977 | 0.76 | TSHR (0.57) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL17036957 | 0.76 | POLB (0.49) | POLBAPEX1HTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210200093-A1 | COATING COMPOSITION FOR PHOTORESIST UNDERLAYER | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2021-07-01 | — | — | US | disclosed |