Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22193449 | 0.97 | TDP1 (0.56) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL811460 | 0.94 | TDP1 (0.48) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL7102222 | 0.92 | TDP1 (0.59) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL4640492 | 0.86 | TSHR (0.64) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1696749 | 0.85 | TDP1 (0.54) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL17036988 | 0.85 | HTT (0.72) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL435195 | 0.84 | TDP1 (0.66) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL18350090 | 0.83 | TSHR (0.64) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL11033460 | 0.83 | HTT (0.74) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL10790604 | 0.83 | TDP1 (0.69) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210200093-A1 | COATING COMPOSITION FOR PHOTORESIST UNDERLAYER | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2021-07-01 | — | — | US | disclosed |