Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790604 | 0.98 | TDP1 (0.69) | TDP1LMNAPOLBAPEX1HTT | |
| SCHEMBL433570 | 0.97 | TDP1 (0.71) | TDP1LMNAPOLBAPEX1HTT | |
| SCHEMBL9647846 | 0.95 | TDP1 (0.69) | TDP1LMNAPOLBAPEX1HTT | |
| SCHEMBL28351135 | 0.95 | TDP1 (0.69) | TDP1LMNAPOLBAPEX1HTT | |
| SCHEMBL9647822 | 0.95 | TDP1 (0.69) | TDP1LMNAPOLBAPEX1HTT | |
| SCHEMBL436276 | 0.93 | LMNA (0.61) | TDP1LMNAPOLBAPEX1HTT | |
| SCHEMBL7102222 | 0.92 | TDP1 (0.59) | TDP1LMNAPOLBAPEX1HTT | |
| SCHEMBL29316020 | 0.91 | TDP1 (0.54) | TDP1LMNAPOLBAPEX1HTT | |
| Dimethylamine SCHEMBL1021289 | 0.89 | LMNA (0.56) | TDP1LMNAPOLBAPEX1HTT | |
| SCHEMBL7102549 | 0.89 | TDP1 (0.50) | TDP1LMNAPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984318-B1 | HIGH REFRACTIVE INDEX MONOMERS AND (CO)POLYMERS PREPARED THEREFROM | OCULENTIS HOLDING BV (NL) | 2015-08-26 | — | — | EP | disclosed |
| US-9103964-B2 | Intraocular lenses essentially free from glistenings | OCULENTIS HOLDING B.V. (NL) | 2015-08-11 | — | — | US | disclosed |
| CN-101405253-B | High refractive index monomers and (co)polymers prepared therefrom | PROCORNEA HOLDING BV | 2012-07-18 | — | — | CN | disclosed |
| WO-2012010918-A2 | OPTICAL DEVICES | MEDICONTUR ORVOSTECHNIKAI KFT. (HU) | 2012-01-26 | — | — | WO | disclosed |
| US-7923520-B2 | High refractive index monomers and (co)polymers prepared therefrom | PROCORNEA HOLDING B.V. (NL) | 2011-04-12 | — | — | US | disclosed |
| EP-1984761-B1 | INTRAOCULAR LENSES ESSENTIALLY FREE FROM GLISTENINGS | PROCORNEA HOLDING BV (NL) | 2011-03-23 | — | — | EP | disclosed |
| US-20110021733-A1 | INTRAOCULAR LENSES ESSENTIALLY FREE FROM GLISTENINGS | PROCORNEA HOLDING B.V. | 2011-01-27 | — | — | US | disclosed |
| CN-101405253-A | High refractive index monomers and (co)polymers prepared therefrom | PROCORNEA HOLDING BV (NL) | 2009-04-08 | — | — | CN | disclosed |
| US-20090054978-A1 | INTRAOCULAR LENSES ESSENTIALLY FREE FROM GLISTENINGS | PROCOMEA HOLDING B.V. | 2009-02-26 | — | — | US | disclosed |
| US-20090023879-A1 | HIGH REFRACTIVE INDEX MONOMERS AND (CO)POLYMERS PREPARED THEREFROM | PROCORNEA HOLDING B.V. | 2009-01-22 | — | — | US | disclosed |
| EP-0313474-B1 | AN OPTICAL ARTICLE EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-12-23 | — | — | EP | disclosed |
| US-4886339-A | MOLECULAR DIPOLES HELD IN POLAR ALIGNMENT BY A CROSSLINKED POLYMERIC BINDER; STABILITY | EASTMAN KODAK COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0313476-A2 | An optical article containing a polymeric matrix exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313475-A2 | An optical article containing a transmission medium exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313474-A2 | An optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| US-4796971-A | CHARGE TRANSFER COMPOUND ON CROSSLINKED MATRIX | EASTMAN KODAK COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| US-4792208-A | POLAR ALIGNED NONCENTROSYMMETRIC MOLECULAR DIPOLES; SULFONYL MOIETY AS ELECTRON ACCEPTOR | EASTMAN KODAK COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0129234-A1 | Electrophotographic elements having barrier layers of crosslinked polymers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4485161-A | Electrophotographic elements having barrier layers of crosslinked polymers of aliphatic or aromatic monomers containing α,β-ethylenically unsaturated carbonyl-containing substituents | EASTMAN KODAK COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| US-4322490-A | Photopolymerizable compositions featuring improved monomers | EASTMAN KODAK COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023879-A1 | HIGH REFRACTIVE INDEX MONOMERS AND (CO)POLYMERS PREPARED THEREFROM | MACF1, FHIT, ALOX5 | TDP1 3586/4885LMNA 2417/4885POLB 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.