SCHEMBL23601690

SCHEMBL23601690

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OCc5cn(CCOCCO[C@H]6OC(CO)[C@@H](O)C(O)C6O)nn5)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.56
GBA1 P04062 2/20 0.55
UGCG Q16739 2/20 0.55
GBA2 Q9HCG7 2/20 0.55
POLA1 P09884 1/20 0.52
PTPN7 P35236 1/20 0.50
DUSP3 P51452 1/20 0.50
CYP46A1 Q9Y6A2 2/20 0.49
HPSE Q9Y251 4/20 0.48
FGF1 P05230 3/20 0.48
FGF2 P09038 3/20 0.48
OSBP P22059 2/20 0.48
USP2 O75604 1/20 0.48
LMNA P02545 1/20 0.48
ABCB1 P08183 1/20 0.48
RORC P51449 1/20 0.48
OSBP2 Q969R2 1/20 0.48
LGALS3 P17931 1/20 0.46
NPC1L1 Q9UHC9 2/20 0.45
APP P05067 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23601842 1.00 POLB (0.56) POLBGBA1UGCGGBA2POLA1
SCHEMBL23601691 0.89 POLB (0.49) POLBGBA1UGCGGBA2POLA1
SCHEMBL23614817 0.87 HPSE (0.61) POLA1HPSEFGF1FGF2LGALS3
SCHEMBL13964924 0.81 POLB (0.62) POLBGBA1UGCGGBA2POLA1
SCHEMBL13469722 0.81 POLB (0.62) POLBGBA1UGCGGBA2POLA1
Cholesterol Glycoside SCHEMBL5953321 0.81 POLB (0.80) POLBGBA1UGCGGBA2POLA1
Cholesterol Glycoside SCHEMBL2838242 0.81 POLB (0.80) POLBGBA1UGCGGBA2POLA1
Cholesterol Glycoside SCHEMBL1357529 0.81 POLB (0.80) POLBGBA1UGCGGBA2POLA1
Cholesterol Glycoside SCHEMBL5257698 0.81 POLB (0.80) POLBGBA1UGCGGBA2POLA1
Cholesterol Glycoside SCHEMBL12695652 0.81 POLB (0.80) POLBGBA1UGCGGBA2POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210196832-A1 TARGETED NANOPREPARATION OF MANNOSE, AND PREPARATION THEREFOR AND APPLICATION THEREOF CHENGDU RIBOCURE PHARMATECH COMPANY LIMITED (CN) 2021-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210196832-A1 TARGETED NANOPREPARATION OF MANNOSE, AND PREPARATION THEREFOR AND APPLICATION THEREOF M6PR, IGF2R, MAN2A1 POLB 4649/4885GBA1 973/4885UGCG 495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.