Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530637 | 0.83 | SIGMAR1 (0.82) | SIGMAR1KCNH2 | |
| Oxalic Acid SCHEMBL4511455 | 0.81 | SIGMAR1 (0.69) | SIGMAR1KCNH2 | |
| SCHEMBL467173 | 0.80 | SIGMAR1 (0.83) | SIGMAR1KCNH2 | |
| SCHEMBL19988158 | 0.80 | SIGMAR1 (0.85) | SIGMAR1KCNH2 | |
| Oxalic Acid SCHEMBL4521956 | 0.80 | SIGMAR1 (0.79) | SIGMAR1KCNH2 | |
| SCHEMBL466869 | 0.80 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| SCHEMBL29558224 | 0.80 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL1897332 | 0.79 | SIGMAR1 (0.98) | SIGMAR1KCNH2 | |
| SCHEMBL467027 | 0.79 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| SCHEMBL4560092 | 0.79 | SIGMAR1 (0.78) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571501-B1 | SIGMA LIGANDS FOR THE PREVENTION AND/OR TREATMENT OF EMESIS INDUCED BY CHEMOTHERAPY OR RADIOTHERAPY | ESTEVE LABOR DR (ES) | 2016-03-02 | — | — | EP | claimed |
| EP-1781618-B1 | SIGMA RECEPTOR INHIBITORS | ESTEVE LABOR DR (ES) | 2012-10-03 | — | — | EP | claimed |
| WO-2011095585-A1 | SIGMA LIGANDS FOR POTENTIATING THE ANALGESIC EFFECT OF OPIOIDS AND OPIATES IN POST-OPERATIVE PAIN AND ATTENUATING THE DEPENDENCY THEREOF | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2011-08-11 | — | — | WO | claimed |
| WO-2011095585-A1 | SIGMA LIGANDS FOR POTENTIATING THE ANALGESIC EFFECT OF OPIOIDS AND OPIATES IN POST-OPERATIVE PAIN AND ATTENUATING THE DEPENDENCY THEREOF | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2011-08-11 | — | — | WO | disclosed |