SCHEMBL23601792

SCHEMBL23601792

Cc1cc2c(cc1F)c(N1CCCc3ccc(F)cc31)nc1nncn12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 5/20 0.36
ROCK1 Q13464 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.32
EGFR P00533 2/20 0.32
PDGFRB P09619 2/20 0.32
KDR P35968 2/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23601791 0.92 STAT3 (0.41) STAT3KMT2AMAPTROCK1SMN1; SMN2
SCHEMBL29909764 0.92 STAT3 (0.41) STAT3KMT2AMAPTROCK1SMN1; SMN2
SCHEMBL23576993 0.89 STAT3 (0.39) STAT3KMT2AMAPTROCK1
SCHEMBL29909952 0.89 STAT3 (0.39) STAT3KMT2AMAPTROCK1
SCHEMBL23601794 0.89 KMT2A (0.51) STAT3KMT2AMAPTROCK1SMN1; SMN2
SCHEMBL29909798 0.83 STAT3 (0.36) STAT3KMT2AROCK1
SCHEMBL23577448 0.83 STAT3 (0.36) STAT3KMT2AROCK1
SCHEMBL29909088 0.81 KMT2A (0.54) STAT3KMT2AMAPTROCK1SMN1; SMN2
SCHEMBL23576636 0.81 KMT2A (0.54) STAT3KMT2AMAPTROCK1SMN1; SMN2
SCHEMBL23601225 0.81 STAT3 (0.36) STAT3KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 WO disclosed