Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.38 |
| ▸ | TUBB | P07437 | 5/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576636 | 0.92 | KMT2A (0.54) | KMT2ASTAT3MAPTTUBB4ATUBB | |
| SCHEMBL29909088 | 0.92 | KMT2A (0.54) | KMT2ASTAT3MAPTTUBB4ATUBB | |
| SCHEMBL23601792 | 0.89 | STAT3 (0.39) | KMT2ASTAT3MAPTTUBB4ATUBB | |
| SCHEMBL23577076 | 0.89 | KMT2A (0.52) | KMT2ASTAT3MAPTTUBB4ATUBB | |
| SCHEMBL29909264 | 0.89 | KMT2A (0.52) | KMT2ASTAT3MAPTTUBB4ATUBB | |
| SCHEMBL23577062 | 0.86 | KMT2A (0.48) | KMT2ASTAT3MAPTTUBB4ATUBB | |
| SCHEMBL23576627 | 0.85 | KMT2A (0.48) | KMT2ASTAT3MAPTTUBB4ATUBB | |
| SCHEMBL29909085 | 0.85 | KMT2A (0.48) | KMT2ASTAT3MAPTTUBB4ATUBB | |
| SCHEMBL23577746 | 0.85 | KMT2A (0.48) | KMT2ASTAT3MAPTTUBB4ATUBB | |
| SCHEMBL23577934 | 0.85 | KMT2A (0.46) | KMT2ASTAT3MAPTTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |