Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601890 | 0.81 | TP53 (0.39) | SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL23576642 | 0.80 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL29909520 | 0.80 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL23601063 | 0.79 | — | — | |
| SCHEMBL23601764 | 0.78 | MAPT (0.30) | SMN1; SMN2MAPT | |
| SCHEMBL23601714 | 0.78 | — | — | |
| SCHEMBL23601777 | 0.77 | TP53 (0.32) | MAPT | |
| SCHEMBL23601373 | 0.75 | — | — | |
| SCHEMBL23601061 | 0.74 | SMN1; SMN2 (0.35) | SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL23601988 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |