SCHEMBL29909520

SCHEMBL29909520

CCN(c1cccc(C#CC2(C)CC2)c1)c1nc2nncn2c2ccc(F)cc12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
MAP3K14 Q99558 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576642 1.00 SMN1; SMN2 (0.31) SMN1; SMN2MAP3K14
SCHEMBL23601988 0.90
SCHEMBL24721236 0.86 PTAFR (0.35) MAP3K14
SCHEMBL29909393 0.86 PTAFR (0.35) MAP3K14
SCHEMBL23601890 0.80 TP53 (0.39) SMN1; SMN2
SCHEMBL23601889 0.80 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL23601699 0.80 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL23601654 0.80
SCHEMBL23577193 0.80
SCHEMBL29909895 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed