Sugi Predict

Sugi Predict / Compounds / SCHEMBL23601946

SCHEMBL23601946

SCHEMBL23601946

c1ccc(-n2c3ccccc3c3cc4c(cc32)c2ccccc2n4-c2nc(-c3ccc4c(c3)oc3ccccc34)nc(-c3ccc4c(c3)oc3ccccc34)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.43
▸ ATM Q13315 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ AHR P35869 2/20 0.35
▸ ALDH1A1 P00352 4/20 0.35
▸ MEN1 O00255 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ MAPT P10636 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ SMN1; SMN2 Q16637 4/20 0.34
▸ PTGER4 P35408 2/20 0.34
▸ LMNA P02545 2/20 0.34
▸ HCRTR1 O43613 1/20 0.34
▸ MMP12 P39900 1/20 0.33
▸ MMP13 P45452 1/20 0.33
▸ TTR P02766 1/20 0.33
▸ SIRT2 Q8IXJ6 1/20 0.32
▸ SIRT1 Q96EB6 1/20 0.32
▸ NPSR1 Q6W5P4 2/20 0.32
▸ CHEK2 O96017 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19769833 0.98 KDM4E (0.41) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL25965889 0.98 KDM4E (0.41) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL25965891 0.98 KDM4E (0.43) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL23602221 0.97 KDM4E (0.40) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL25965886 0.96 KDM4E (0.39) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL22049222 0.94 KDM4E (0.38) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL19769835 0.94 ATM (0.38) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL22049450 0.94 KDM4E (0.37) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL25965850 0.94 KDM4E (0.40) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL19769736 0.94 KDM4E (0.40) KDM4EATML3MBTL1AHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284526-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-09-07 — — US disclosed
US-20230284526-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-09-07 — — US disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 — — US disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 — — US disclosed
US-20220416177-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-12-29 — — US disclosed
WO-2021131755-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME 日鉄ケミカル＆マテリアル株式会社 2021-07-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, EPB41, EPB41L2 KDM4E 1097/4885ATM 3975/4885L3MBTL1 877/4885
US-20220416177-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NR4A3, NR4A1, NR4A2 KDM4E 594/4885ATM 4358/4885L3MBTL1 532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.