Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2308553 | 0.88 | DRD3 (1.00) | DRD3KCNH2HRH1DRD2 | |
| Hydrochloric Acid SCHEMBL2308190 | 0.88 | DRD3 (0.98) | DRD3KCNH2HRH1DRD2 | |
| SCHEMBL5555680 | 0.75 | DRD3 (0.79) | DRD3KCNH2HRH1DRD2 | |
| SCHEMBL2310034 | 0.74 | DRD3 (1.00) | DRD3KCNH2HRH1DRD2 | |
| Hydrochloric Acid SCHEMBL2312980 | 0.73 | DRD3 (0.98) | DRD3KCNH2HRH1DRD2 | |
| SCHEMBL2313348 | 0.73 | DRD3 (1.00) | DRD3KCNH2HRH1 | |
| SCHEMBL2312613 | 0.72 | DRD3 (1.00) | DRD3KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL2309868 | 0.72 | DRD3 (0.98) | DRD3KCNH2HRH1 | |
| SCHEMBL2307625 | 0.71 | DRD3 (1.00) | DRD3KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL2313983 | 0.70 | DRD3 (0.98) | DRD3KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751163-B1 | BENZAZEPINE COMPOUNDS HAVING AFFINITY FOR DOPAMINE D3 RECEPTOR AND USES THEREOF | GLAXO GROUP LTD (GB) | 2011-08-10 | — | — | EP | claimed |