Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 15/20 | 0.79 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2308180 | 0.89 | DRD3 (1.00) | DRD3KCNH2HRH1 | |
| Hydrochloric Acid SCHEMBL2308563 | 0.88 | DRD3 (0.98) | DRD3KCNH2HRH1 | |
| SCHEMBL2312613 | 0.86 | DRD3 (1.00) | DRD3KCNH2HRH1 | |
| SCHEMBL2308553 | 0.85 | DRD3 (1.00) | DRD3KCNH2HRH1DRD2 | |
| Hydrochloric Acid SCHEMBL2308190 | 0.84 | DRD3 (0.98) | DRD3KCNH2HRH1DRD2 | |
| SCHEMBL5551758 | 0.81 | DRD3 (0.84) | DRD3KCNH2HRH1 | |
| SCHEMBL2309167 | 0.76 | DRD3 (1.00) | DRD3KCNH2HRH1DRD2 | |
| Hydrochloric Acid SCHEMBL2309592 | 0.75 | DRD3 (0.98) | DRD3KCNH2HRH1DRD2 | |
| SCHEMBL2360197 | 0.75 | DRD3 (0.79) | DRD3KCNH2HRH1DRD2 | |
| SCHEMBL2315080 | 0.75 | DRD3 (1.00) | DRD3KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751163-A2 | COMPOUNDS HAVING AFFINITY FOR DOPAMINE D3 RECEPTOR AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005118549-A2 | COMPOUNDS HAVING AFFINITY FOR DOPAMINE D3 RECEPTOR AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2005-12-15 | — | — | WO | disclosed |