Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763469 | 0.99 | ESR1 (0.51) | TSHRMAPK1CYP3A4TP53ESR1 | |
| SCHEMBL15842178 | 0.95 | ESR1 (0.54) | TSHRMAPK1CYP3A4TP53ESR1 | |
| SCHEMBL13836975 | 0.84 | TSHR (0.49) | TSHRMAPK1CYP3A4TP53ESR1 | |
| SCHEMBL1236215 | 0.84 | ALDH1A1 (0.55) | TSHRMAPK1CYP3A4TP53ESR1 | |
| SCHEMBL5778009 | 0.83 | CA12 (0.51) | CYP3A4ESR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL30234144 | 0.83 | CA12 (0.51) | CYP3A4ESR1LMNAALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9520152 | 0.81 | CA12 (0.50) | ESR1LMNAALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL8924303 | 0.81 | ALDH1A1 (0.48) | TSHRMAPK1CYP3A4TP53ESR1 | |
| SCHEMBL8924301 | 0.81 | ALDH1A1 (0.48) | TSHRMAPK1CYP3A4TP53ESR1 | |
| SCHEMBL23189019 | 0.81 | TSHR (0.50) | TSHRMAPK1CYP3A4TP53ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295930-A1 | NOVEL PROCESS FOR THE PREPARATION OF CIS-NUCLEOSIDE DERIVATIVE | MYLAN LABORATORIES LIMITED (IN) | 2012-11-22 | — | — | US | claimed |
| WO-2011095987-A1 | NOVEL PROCESS FOR THE PREPARATION OF CIS-NUCLEOSIDE DERIVATIVE | MATRIX LABORATORIES LTD. (IN) | 2011-08-11 | — | — | WO | claimed |
| US-20120295930-A1 | NOVEL PROCESS FOR THE PREPARATION OF CIS-NUCLEOSIDE DERIVATIVE | MYLAN LABORATORIES LIMITED (IN) | 2012-11-22 | — | — | US | disclosed |
| WO-2011095987-A1 | NOVEL PROCESS FOR THE PREPARATION OF CIS-NUCLEOSIDE DERIVATIVE | MATRIX LABORATORIES LTD. (IN) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295930-A1 | NOVEL PROCESS FOR THE PREPARATION OF CIS-NUCLEOSIDE DERIVATIVE | DDX1, NSUN2, SLC29A1 | TSHR 3024/4885MAPK1 2881/4885CYP3A4 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.