Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23578464 | 0.99 | DGAT1 (0.50) | DGAT1KCNH2ADORA2APDE4APDE4B | |
| Hydrochloric Acid SCHEMBL29830413 | 0.99 | DGAT1 (0.50) | DGAT1KCNH2ADORA2APDE4APDE4B | |
| SCHEMBL23602269 | 0.88 | DGAT1 (0.47) | DGAT1KCNH2ADORA2APDE4APDE4B | |
| Hydrochloric Acid SCHEMBL29829711 | 0.87 | DGAT1 (0.46) | DGAT1KCNH2ADORA2APDE4APDE4B | |
| Hydrochloric Acid SCHEMBL28803631 | 0.87 | DGAT1 (0.46) | DGAT1KCNH2ADORA2APDE4APDE4B | |
| SCHEMBL23603147 | 0.87 | PDE4A (0.46) | DGAT1KCNH2ADORA2APDE4APDE4B | |
| SCHEMBL29830004 | 0.86 | HRH3 (0.54) | DGAT1KCNH2ADORA2APDE4APDE4B | |
| SCHEMBL23602297 | 0.86 | HRH3 (0.54) | DGAT1KCNH2ADORA2APDE4APDE4B | |
| SCHEMBL23602974 | 0.86 | DGAT1 (0.50) | DGAT1KCNH2ADORA2APDE10AHRH3 | |
| Hydrochloric Acid SCHEMBL23578483 | 0.86 | PDE4A (0.46) | DGAT1KCNH2ADORA2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081304-B1 | ANTIBACTERIAL QUINOLINES | TECNIMEDE SOCIEDADE TECNICO MEDICINAL SA (PT) | 2024-03-06 | — | — | EP | claimed |
| WO-2021130732-A1 | ANTIBACTERIAL QUINOLINES | TECNIMEDE - Sociedade Técnico-medicinal, SA (PT) | 2021-07-01 | — | — | WO | disclosed |