Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.55 |
| ▸ | RAB9A | P51151 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632197 | 0.84 | NPC1 (0.46) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL30376133 | 0.84 | NPC1 (0.46) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL190246 | 0.83 | NPC1 (0.52) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5692763 | 0.82 | NPC1 (0.45) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL1857119 | 0.82 | NPC1 (0.45) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL2862830 | 0.82 | NPC1 (0.49) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL4125702 | 0.81 | NPC1 (0.50) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11888091 | 0.79 | KMT2A (0.46) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL1856772 | 0.77 | CREBBP (0.47) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11949099 | 0.77 | ALDH1A1 (0.46) | NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021129584-A1 | PD-L1 ANTAGONIST COMPOUND | 杭州阿诺生物医药科技有限公司 | 2021-07-01 | — | — | WO | disclosed |