Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.70 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.70 |
| ▸ | PDCD1LG2 | Q9BQ51 | 18/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24613385 | 0.89 | CD274 (0.82) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23948832 | 0.89 | CD274 (0.82) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL24613690 | 0.89 | CD274 (0.82) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL23949705 | 0.85 | CD274 (0.82) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL24613255 | 0.85 | CD274 (0.82) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL25963581 | 0.84 | CD274 (0.75) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL24613772 | 0.82 | CD274 (0.71) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL25965651 | 0.82 | CD274 (0.71) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21507114 | 0.81 | CD274 (1.00) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL21290802 | 0.79 | CD274 (1.00) | CD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021129584-A1 | PD-L1 ANTAGONIST COMPOUND | 杭州阿诺生物医药科技有限公司 | 2021-07-01 | — | — | WO | disclosed |