Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30044661 | 1.00 | PIK3CD (0.46) | PIK3CDPDE4BHPGDSCHEK2PIK3CA | |
| SCHEMBL23605796 | 0.84 | PIK3CD (0.52) | PIK3CDCHEK2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL23605456 | 0.83 | PDE4B (0.47) | PIK3CDPDE4BHPGDSCHEK2GPR119 | |
| SCHEMBL17418061 | 0.79 | PDE4B (0.46) | PIK3CDPDE4BHPGDSCHEK2PIK3CA | |
| SCHEMBL17418062 | 0.79 | PDE4B (0.46) | PIK3CDPDE4BHPGDSCHEK2PIK3CA | |
| SCHEMBL3133723 | 0.79 | PIK3CD (0.56) | PIK3CDPDE4BPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2457829 | 0.79 | PIK3CD (0.56) | PIK3CDPDE4BPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3134760 | 0.79 | PIK3CD (0.56) | PIK3CDPDE4BPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26668382 | 0.78 | GPR119 (0.53) | PIK3CDPDE4BCHEK2PIK3CAPIK3CB | |
| SCHEMBL26665879 | 0.78 | GPR119 (0.53) | PIK3CDPDE4BCHEK2PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133894-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2021-07-01 | — | — | WO | disclosed |