Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | RAB9A | P51151 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | TOP1 | P11387 | 2/20 | 0.67 |
| ▸ | DHODH | Q02127 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 4/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242970 | 0.84 | CNR1 (0.69) | CNR1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL4912955 | 0.84 | DHODH (0.76) | CNR1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL4918642 | 0.84 | HTT (0.76) | CNR1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL30553297 | 0.84 | RAB9A (0.70) | CNR1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL19194695 | 0.84 | SCD (0.66) | CNR1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL17433366 | 0.84 | TOP1 (0.64) | CNR1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL17770342 | 0.84 | DHODH (0.76) | CNR1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL17178426 | 0.84 | RAB9A (0.69) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22130163 | 0.84 | RAB9A (0.69) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13236116 | 0.84 | NPC1 (0.76) | ALDH1A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230103415-A1 | SMARCA INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-04-06 | — | — | US | disclosed |
| WO-2021133917-A1 | SMARCA INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230103415-A1 | SMARCA INHIBITORS AND USES THEREOF | SMARCC1, SMARCE1, SMARCA1 | CNR1 4708/4885ALDH1A1 3416/4885NPC1 2800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.