Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23608949 | 0.77 | CYP19A1 (0.44) | KDM4EMAPK1ALDH1A1TP53LMNA | |
| SCHEMBL23609133 | 0.74 | DRD4 (0.48) | KDM4EALDH1A1CYP19A1CSNK2A2FGFR2 | |
| SCHEMBL23608962 | 0.72 | IRAK1 (0.39) | KDM4EALDH1A1SMN1; SMN2EGLN3HTT | |
| SCHEMBL23875581 | 0.72 | CYP19A1 (0.51) | KDM4EMAPTMAPK1ALDH1A1TP53 | |
| SCHEMBL23609126 | 0.71 | CYP19A1 (0.40) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19426727 | 0.71 | APP (0.38) | KDR | |
| SCHEMBL29265667 | 0.70 | KDR (0.36) | ALDH1A1KDRHPGDKMT2A | |
| SCHEMBL17840921 | 0.70 | KDM4E (0.46) | KDM4EMAPK1ALDH1A1LMNARAB9A | |
| SCHEMBL12893079 | 0.70 | CHRNB2 (0.43) | ALDH1A1HTTKDR | |
| SCHEMBL99680 | 0.69 | CACNA1C (0.51) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |