Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609004 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23608978 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609257 | 0.81 | KDM4E (0.41) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL29974861 | 0.81 | KDM4E (0.41) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609238 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23579458 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23609298 | 0.74 | PDE5A (0.49) | KDM4EMAPTLMNAALDH1A1TDP1 | |
| SCHEMBL23609429 | 0.74 | PGK1 (0.45) | SMN1; SMN2HTTMAPTLMNAALDH1A1 | |
| SCHEMBL23609386 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTKDM4EMAPTLMNA | |
| SCHEMBL23875581 | 0.72 | CYP19A1 (0.51) | SMN1; SMN2HTTKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |