Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609309 | 0.89 | MAPT (0.77) | MAPTPOLBPKMALDH1A1RAB9A | |
| SCHEMBL29973542 | 0.89 | MAPT (0.77) | MAPTPOLBPKMALDH1A1RAB9A | |
| SCHEMBL21616845 | 0.84 | MAPT (0.60) | MAPTPOLBPKMALDH1A1HRH3 | |
| SCHEMBL2307734 | 0.81 | MAPT (0.66) | MAPTPOLBPKMALDH1A1RAB9A | |
| SCHEMBL23671494 | 0.80 | BACE1 (0.63) | MAPTPOLBPKMALDH1A1HRH3 | |
| SCHEMBL17678258 | 0.80 | MAPT (0.61) | MAPTPOLBPKMALDH1A1HRH3 | |
| SCHEMBL3995356 | 0.79 | HRH3 (0.57) | MAPTPOLBPKMALDH1A1HRH3 | |
| SCHEMBL6232184 | 0.78 | MAPT (0.68) | MAPTPOLBPKMALDH1A1HRH3 | |
| SCHEMBL23609085 | 0.78 | MAPT (0.53) | MAPTPOLBPKMALDH1A1HRH3 | |
| SCHEMBL17678243 | 0.78 | HRH3 (0.55) | MAPTPOLBPKMALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |