Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 15/20 | 0.46 |
| ▸ | CNR1 | P21554 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15097974 | 0.91 | CNR2 (0.56) | ALDH1A1CNR2CNR1CYP1A2HPGD | |
| SCHEMBL15092043 | 0.89 | CNR2 (0.44) | ALDH1A1CNR2CNR1CYP1A2HPGD | |
| SCHEMBL2359903 | 0.89 | CNR2 (0.47) | ALDH1A1CNR2CNR1CYP1A2HPGD | |
| SCHEMBL2360651 | 0.87 | CNR2 (0.47) | ALDH1A1CNR2CNR1CYP1A2HPGD | |
| SCHEMBL15097964 | 0.87 | CNR2 (0.54) | ALDH1A1CNR2CNR1CYP1A2HPGD | |
| SCHEMBL12443332 | 0.86 | CNR2 (0.58) | ALDH1A1CNR2CNR1CYP1A2HPGD | |
| SCHEMBL12443765 | 0.83 | CNR2 (0.56) | ALDH1A1CNR2CNR1CYP1A2HPGD | |
| SCHEMBL12443175 | 0.82 | CNR2 (0.43) | ALDH1A1CNR2CNR1CYP1A2HPGD | |
| SCHEMBL2359543 | 0.82 | CNR2 (0.57) | ALDH1A1CNR2CNR1CYP1A2HPGD | |
| SCHEMBL15098326 | 0.82 | CNR1 (0.41) | CNR2CNR1CYP1A2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130178453-A1 | Cannabinoid Agonists | IRONWOOD PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130178453-A1 | Cannabinoid Agonists | IRONWOOD PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130178453-A1 | Cannabinoid Agonists | IRONWOOD PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| WO-2011100359-A1 | CANNABINOID AGONISTS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178453-A1 | Cannabinoid Agonists | CNR2, CNR1, GPR18 | ALDH1A1 2110/4885CNR2 1/4885CNR1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.