Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23612188 | 0.88 | MPO (0.43) | MPOMAPTMEN1RECQLKMT2A | |
| SCHEMBL23612219 | 0.78 | MPO (0.36) | MPOMAPTMEN1RECQLKMT2A | |
| SCHEMBL16513354 | 0.77 | MPO (0.60) | MPOMAPTMEN1RECQLKMT2A | |
| SCHEMBL23612248 | 0.76 | DDB1 (0.49) | MAPTALDH1A1 | |
| SCHEMBL174612 | 0.74 | F2 (0.41) | MPOMAPTMEN1RECQLKMT2A | |
| SCHEMBL16975322 | 0.74 | MPO (0.48) | MPOMAPTMEN1RECQLKMT2A | |
| SCHEMBL163689 | 0.73 | — | — | |
| SCHEMBL21639876 | 0.73 | F2 (0.38) | MAPTMEN1RECQLKMT2ATDP1 | |
| SCHEMBL22619640 | 0.72 | GAA (0.46) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL30839437 | 0.72 | GAA (0.46) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021138434-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2021-07-08 | — | — | WO | disclosed |