Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24419465 | 0.91 | EPHX1 (0.42) | SHBGEPHX1TSHREPHX2NAAA | |
| SCHEMBL24219174 | 0.87 | MEN1 (0.39) | SHBGMEN1KMT2ABCHEEPHX1 | |
| SCHEMBL9202709 | 0.86 | SHBG (0.42) | SHBGMEN1KMT2ABCHEEPHX1 | |
| SCHEMBL9205502 | 0.84 | EPHX1 (0.41) | MEN1KMT2ABCHEEPHX1TSHR | |
| SCHEMBL9213609 | 0.83 | MEN1 (0.39) | MEN1KMT2ABCHEEPHX1TSHR | |
| SCHEMBL9206047 | 0.82 | BCHE (0.41) | SHBGMEN1KMT2ABCHEEPHX1 | |
| SCHEMBL9213089 | 0.81 | TSHR (0.38) | MEN1KMT2AEPHX1TSHREPHX2 | |
| SCHEMBL9212423 | 0.80 | EPHX1 (0.44) | EPHX1TSHREPHX2NAAASIGMAR1 | |
| SCHEMBL26910244 | 0.80 | MEN1 (0.42) | SHBGMEN1KMT2ABCHEEPHX1 | |
| SCHEMBL9207776 | 0.78 | EPHX1 (0.41) | EPHX1TSHREPHX2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284706-A1 | COMPOSITIONS AND METHODS FOR TARGETED CYTOKINE DELIVERY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-09-16 | — | — | US | disclosed |
| US-11053293-B2 | Compositions and methods for targeted cytokine delivery | WASHINGTON UNIVERSITY | 2021-07-06 | — | — | US | disclosed |