Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.35 |
| ▸ | DPP4 | P27487 | 7/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911096 | 0.88 | L3MBTL1 (0.63) | L3MBTL1ARG1ARG2MAPTALDH1A1 | |
| SCHEMBL1007971 | 0.79 | — | — | |
| SCHEMBL29973401 | 0.78 | L3MBTL1 (0.50) | L3MBTL1ARG1ARG2MAPTALDH1A1 | |
| SCHEMBL11598668 | 0.75 | L3MBTL1 (0.77) | L3MBTL1MAPTALDH1A1POLBKDM4E | |
| SCHEMBL8860545 | 0.75 | L3MBTL1 (0.77) | L3MBTL1MAPTALDH1A1POLBKDM4E | |
| SCHEMBL11357218 | 0.75 | GAA (0.36) | L3MBTL1ALDH1A1POLBKDM4E | |
| SCHEMBL30701355 | 0.74 | L3MBTL1 (0.47) | L3MBTL1ARG1ARG2MAPTALDH1A1 | |
| SCHEMBL7428460 | 0.74 | CYP1A2 (0.55) | L3MBTL1DPP7DPP4ARG1ARG2 | |
| SCHEMBL11668210 | 0.72 | CYP1A2 (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7772650 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533645-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100373-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-08-18 | — | — | WO | disclosed |