Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26455581 | 0.93 | HTT (0.41) | RECQLHTTALDH1A1KDM4EMAPT | |
| SCHEMBL736240 | 0.93 | HTT (0.41) | RECQLHTTALDH1A1KDM4EMAPT | |
| SCHEMBL18745619 | 0.86 | HTT (0.38) | RECQLHTTALDH1A1KDM4EMAPT | |
| SCHEMBL19419597 | 0.84 | CHKA (0.44) | HTTALDH1A1KDM4EHTR7 | |
| SCHEMBL19543019 | 0.82 | HTR7 (0.34) | HTR7 | |
| SCHEMBL19543661 | 0.82 | HTR7 (0.34) | HTR7 | |
| SCHEMBL11840677 | 0.82 | — | — | |
| SCHEMBL12092353 | 0.82 | HTR7 (0.34) | HTR7 | |
| SCHEMBL16800195 | 0.81 | TSHR (0.33) | HTR7 | |
| SCHEMBL23774964 | 0.78 | KDM4E (0.32) | HTTALDH1A1KDM4EMAPTMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053238-B2 | Benzimidazole derivatives, preparation methods and uses thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053238-B2 | Benzimidazole derivatives, preparation methods and uses thereof | CDK6, CDK4, CDK3 | RECQL 1663/4885HTT 4208/4885ALDH1A1 1568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.