Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14957212 | 1.00 | GAA (0.46) | GAAALDH1A1LMNAGLATHRB | |
| SCHEMBL19647069 | 1.00 | GAA (0.46) | GAAALDH1A1LMNAGLATHRB | |
| SCHEMBL20160081 | 0.90 | ALDH1A1 (0.53) | GAAALDH1A1LMNATHRBCYP2C9 | |
| SCHEMBL20346848 | 0.90 | ALDH1A1 (0.53) | GAAALDH1A1LMNATHRBCYP2C9 | |
| SCHEMBL903575 | 0.90 | ALDH1A1 (0.53) | GAAALDH1A1LMNATHRBCYP2C9 | |
| Trifluoroacetic Acid SCHEMBL13731716 | 0.86 | ALDH1A1 (0.48) | GAAALDH1A1LMNATHRBCYP2C9 | |
| SCHEMBL14962706 | 0.85 | ATM (0.51) | GAAALDH1A1LMNAGLATHRB | |
| SCHEMBL903526 | 0.83 | ALDH1A1 (0.45) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL16197554 | 0.83 | MME (0.47) | ALDH1A1LMNATHRBCYP2C9CYP2C19 | |
| SCHEMBL15292153 | 0.83 | MME (0.47) | ALDH1A1LMNATHRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327027-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2021-07-07 | — | — | EP | disclosed |