Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CBX7 | O95931 | 3/20 | 0.49 |
| ▸ | CDYL | Q9Y232 | 3/20 | 0.49 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 3/20 | 0.49 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22761146 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACBX7CDYL | |
| SCHEMBL23615673 | 0.95 | CBX7 (0.51) | ALDH1A1MEN1KMT2ACBX7CDYL | |
| SCHEMBL23615751 | 0.95 | CBX7 (0.51) | ALDH1A1MEN1KMT2ACBX7CDYL | |
| SCHEMBL23615744 | 0.94 | TP53 (0.49) | ALDH1A1MEN1KMT2ACBX7CDYL | |
| SCHEMBL22761257 | 0.94 | TP53 (0.49) | ALDH1A1MEN1KMT2ACBX7CDYL | |
| SCHEMBL23615771 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ACBX7CDYL | |
| SCHEMBL23615647 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ACBX7CDYL | |
| SCHEMBL23615704 | 0.90 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL22761201 | 0.90 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL23615757 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ACBX7CDYL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634957-B1 | NMDA RECEPTOR MODULATORS, COMPOSITIONS COMPRISING SAME AND USE OF THESE COMPOUNDS IN THE TREATMENT OF DISEASES INVOLVING THE CENTRAL NERVOUS SYSTEM | ADPUERIVITAM (FR) | 2021-07-07 | — | — | EP | disclosed |