Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 12/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361353 | 1.00 | GBA1 (0.43) | GBA1EPHX2CNR2NAAA | |
| SCHEMBL13954685 | 0.98 | GBA1 (0.46) | GBA1EPHX2CNR2NAAA | |
| SCHEMBL14119588 | 0.98 | GBA1 (0.46) | GBA1EPHX2CNR2NAAA | |
| SCHEMBL13455823 | 0.98 | GBA1 (0.46) | GBA1EPHX2CNR2NAAA | |
| SCHEMBL10076752 | 0.95 | CNR2 (0.36) | GBA1EPHX2CNR2NAAA | |
| SCHEMBL8970146 | 0.89 | GBA1 (0.46) | GBA1EPHX2 | |
| SCHEMBL11187287 | 0.87 | GBA1 (0.48) | GBA1EPHX2NAAA | |
| SCHEMBL8970220 | 0.87 | GBA1 (0.48) | GBA1EPHX2NAAA | |
| SCHEMBL8970521 | 0.87 | GBA1 (0.48) | GBA1EPHX2NAAA | |
| SCHEMBL8969403 | 0.87 | GBA1 (0.48) | GBA1EPHX2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786913-B1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-08-17 | — | — | EP | disclosed |