Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 19/20 | 0.56 |
| ▸ | MTOR | P42345 | 18/20 | 0.56 |
| ▸ | ATR | Q13535 | 4/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21851164 | 0.85 | ATM (0.54) | ATMMTORATRPIK3CAKCNH2 | |
| SCHEMBL21851127 | 0.84 | ATM (0.57) | ATMMTORATRPIK3CAKCNH2 | |
| SCHEMBL21851215 | 0.83 | ATM (0.53) | ATMMTORATRPIK3CAKCNH2 | |
| SCHEMBL23615854 | 0.83 | ATM (0.57) | ATMMTORATRPIK3CAKCNH2 | |
| SCHEMBL21851043 | 0.82 | ATM (0.58) | ATMMTORATRPIK3CAKCNH2 | |
| SCHEMBL21851097 | 0.82 | ATM (0.56) | ATMMTORATRPIK3CAKCNH2 | |
| SCHEMBL21851066 | 0.81 | ATM (0.51) | ATMMTORATRPIK3CAKCNH2 | |
| SCHEMBL21851063 | 0.80 | ATM (0.51) | ATMMTORATRPIK3CAKCNH2 | |
| SCHEMBL29968726 | 0.79 | ATM (0.53) | ATMMTORATRPIK3CA | |
| SCHEMBL24221452 | 0.79 | ATM (0.52) | ATMMTORATRPIK3CAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845532-B1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC (CN) | 2022-12-21 | — | — | EP | disclosed |
| EP-3845532-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2021-07-07 | — | — | EP | disclosed |