Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266728 | 0.85 | POLB (0.45) | POLBMEN1KMT2ACYP2C9GAA | |
| SCHEMBL13275155 | 0.85 | POLB (0.44) | POLBMEN1KMT2ACYP2C9HSP90AA1 | |
| SCHEMBL13274726 | 0.83 | POLB (0.42) | POLBMEN1KMT2ACYP2C9GAA | |
| SCHEMBL13274951 | 0.82 | SMN1; SMN2 (0.42) | POLBKMT2ACYP2C9GAAALDH1A1 | |
| SCHEMBL2268843 | 0.81 | CYP2C9 (0.53) | POLBMEN1KMT2ACYP2C9GAA | |
| SCHEMBL2275065 | 0.79 | GAA (0.42) | POLBMEN1KMT2ACYP2C9GAA | |
| SCHEMBL2270343 | 0.78 | JAK3 (0.33) | MEN1KMT2AEGLN1TP53 | |
| SCHEMBL13274578 | 0.77 | GAA (0.44) | POLBMEN1KMT2ACYP2C9GAA | |
| SCHEMBL13274806 | 0.76 | L3MBTL1 (0.35) | MEN1KMT2ACYP2C9GRM2HTT | |
| SCHEMBL2222125 | 0.75 | POLB (0.55) | POLBMEN1KMT2ACYP2C9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084402-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |