Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041805 | 0.77 | STAT5B (0.45) | ALDH1A1HDAC1HDAC2FURINHDAC3 | |
| SCHEMBL26921523 | 0.66 | HDAC1 (0.51) | CYP1A2HDAC1HDAC2NPC1HDAC3 | |
| SCHEMBL650708 | 0.65 | MAPT (0.47) | CYP1A2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL29922726 | 0.65 | MAPT (0.47) | CYP1A2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL6201094 | 0.64 | MAPT (0.52) | CYP1A2ALDH1A1CYP2C9CYP2C19MAPT | |
| Hydrochloric Acid SCHEMBL11812357 | 0.63 | MAPT (0.46) | CYP1A2ALDH1A1CYP2C9CYP2C19MAPT | |
| Hydrochloric Acid SCHEMBL28088636 | 0.63 | MAPT (0.46) | CYP1A2ALDH1A1CYP2C9CYP2C19MAPT | |
| Ammonia Solution, Strong SCHEMBL3076461 | 0.63 | MAPT (0.46) | CYP1A2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL27899216 | 0.62 | MAPT (0.48) | CYP1A2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL3628342 | 0.62 | IDO1 (0.47) | CYP1A2ALDH1A1CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523297-B1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | UNIV BERLIN FREIE (DE) | 2021-07-07 | — | — | EP | disclosed |