Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT5B | P51692 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20048205 | 0.80 | MEN1 (0.30) | HSD17B10MEN1RECQLKMT2A | |
| SCHEMBL23615918 | 0.79 | — | — | |
| SCHEMBL20048219 | 0.68 | STAT5B (0.44) | STAT5B | |
| SCHEMBL5670776 | 0.61 | GLA (0.43) | STAT5BPOLBTSHR | |
| SCHEMBL20041766 | 0.60 | STAT5B (0.44) | STAT5BTSHR | |
| SCHEMBL10000161 | 0.59 | NPSR1 (0.46) | STAT5BPOLBKMT2ATSHR | |
| SCHEMBL22213898 | 0.58 | NPSR1 (0.45) | STAT5BPOLBKMT2ATSHR | |
| SCHEMBL22096015 | 0.57 | STAT5B (1.00) | STAT5BHSD17B10MAPTTSHR | |
| SCHEMBL17950597 | 0.57 | NPSR1 (0.48) | STAT5BPOLBHSD17B10MEN1RECQL | |
| SCHEMBL13343501 | 0.57 | KMT2A (0.50) | POLBKMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523297-B1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | UNIV BERLIN FREIE (DE) | 2021-07-07 | — | — | EP | disclosed |