SCHEMBL20041766

SCHEMBL20041766

COC(=O)c1nonc1NCN(N)/C=N\N

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
STAT5B P51692 1/20 0.44
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20048208 0.72 STAT5B (0.39) STAT5B
SCHEMBL23615869 0.71 STAT5B (0.46) STAT5BTSHRNPSR1
SCHEMBL20041810 0.68 STAT5B (0.42) STAT5B
SCHEMBL13343501 0.62 KMT2A (0.50) TSHRNPSR1
SCHEMBL22096015 0.61 STAT5B (1.00) STAT5BTSHR
SCHEMBL10000161 0.61 NPSR1 (0.46) STAT5BTSHRNPSR1
SCHEMBL23615919 0.60 STAT5B (0.40) STAT5BTSHR
SCHEMBL22213898 0.60 NPSR1 (0.45) STAT5BTSHRNPSR1
SCHEMBL17950597 0.59 NPSR1 (0.48) STAT5BTSHRNPSR1
SCHEMBL8936043 0.57 NPSR1 (0.42) STAT5BTSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3523297-B1 NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER UNIV BERLIN FREIE (DE) 2021-07-07 EP disclosed
WO-2018065536-A1 NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER FREIE UNIVERSITÄT BERLIN (DE) 2018-04-12 WO disclosed
EP-3305783-A1 NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER Freie Universität Berlin (DE) 2018-04-11 EP disclosed