Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.38 |
| ▸ | MAOB | P27338 | 11/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21791772 | 0.87 | NPC1 (0.49) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL23766643 | 0.85 | NPC1 (0.47) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL17552746 | 0.79 | NPC1 (0.55) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL21791777 | 0.79 | NPC1 (0.42) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL11964382 | 0.77 | NPC1 (0.56) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL25875894 | 0.76 | NPC1 (0.42) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL25875768 | 0.75 | NPC1 (0.37) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL825336 | 0.75 | NPC1 (0.58) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL23766666 | 0.74 | CNR2 (0.38) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL14706810 | 0.73 | NPC1 (0.56) | NPC1RAB9AMAPTHRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845579-A1 | FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME | DAIKIN INDUSTRIES, LTD. (JP) | 2021-07-07 | — | — | EP | disclosed |