Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328649 | 0.87 | KDM4E (0.44) | KDM4EL3MBTL1ATMPTGER4EDNRA | |
| SCHEMBL15382706 | 0.83 | KDM4E (0.40) | KDM4EL3MBTL1ATMPTGER4EDNRA | |
| SCHEMBL22990095 | 0.82 | KDM4E (0.37) | KDM4EL3MBTL1ATMEDNRAEDNRB | |
| SCHEMBL26713816 | 0.81 | KDM4E (0.46) | KDM4EL3MBTL1ATMPTGER4AKR1C4 | |
| SCHEMBL21610874 | 0.81 | KDM4E (0.43) | KDM4EL3MBTL1ATMPTGER4EDNRA | |
| SCHEMBL21965264 | 0.81 | KDM4E (0.43) | KDM4EL3MBTL1ATMPTGER4EDNRA | |
| SCHEMBL22912383 | 0.80 | KDM4E (0.38) | KDM4EL3MBTL1ATMPTGER4EDNRA | |
| SCHEMBL10348850 | 0.79 | L3MBTL1 (0.64) | KDM4EL3MBTL1ATMPTGER4EDNRA | |
| SCHEMBL10331554 | 0.79 | L3MBTL1 (0.64) | KDM4EL3MBTL1ATMPTGER4EDNRA | |
| SCHEMBL10331509 | 0.79 | L3MBTL1 (0.64) | KDM4EL3MBTL1ATMPTGER4EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845545-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2021-07-07 | — | — | EP | disclosed |