Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6649890 | 0.86 | HTT (0.78) | HTTP2RX7HPGDALDH1A1KMT2A | |
| SCHEMBL18967804 | 0.85 | P2RX7 (0.58) | HTTP2RX7HPGDALDH1A1KMT2A | |
| SCHEMBL19208154 | 0.81 | P2RX7 (0.53) | HTTP2RX7KMT2A | |
| SCHEMBL29781846 | 0.81 | P2RX7 (0.53) | HTTP2RX7KMT2A | |
| SCHEMBL19208424 | 0.81 | P2RX7 (0.56) | HTTP2RX7ALDH1A1KMT2A | |
| SCHEMBL19208100 | 0.81 | P2RX7 (0.55) | HTTP2RX7KMT2A | |
| SCHEMBL29781973 | 0.81 | P2RX7 (0.55) | HTTP2RX7KMT2A | |
| SCHEMBL19208108 | 0.80 | P2RX7 (0.56) | HTTP2RX7KMT2A | |
| SCHEMBL29781841 | 0.80 | P2RX7 (0.56) | HTTP2RX7KMT2A | |
| SCHEMBL19208558 | 0.80 | P2RX7 (0.55) | HTTP2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |