Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 14/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 3/20 | 0.36 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545179 | 0.94 | BRD4 (0.38) | CFDBRD4CREBBPPPIDBCHE | |
| SCHEMBL21438039 | 0.93 | CFD (0.43) | CFDBRD4CREBBPPPIDF11 | |
| SCHEMBL21455196 | 0.93 | CFD (0.41) | CFDBRD4CREBBPPPIDF11 | |
| SCHEMBL23616931 | 0.93 | CFD (0.41) | CFDBRD4CREBBPPPIDF11 | |
| SCHEMBL25880899 | 0.93 | CFD (0.41) | CFDBRD4CREBBPPPIDF11 | |
| SCHEMBL21437824 | 0.92 | CFD (0.41) | CFDBRD4CREBBPPPIDF11 | |
| SCHEMBL23616932 | 0.92 | CFD (0.41) | CFDBRD4CREBBPPPIDF11 | |
| SCHEMBL25881885 | 0.92 | BRD4 (0.36) | CFDBRD4CREBBPPPIDBCHE | |
| SCHEMBL21545298 | 0.92 | CFD (0.41) | CFDBRD4CREBBPPPIDF11 | |
| SCHEMBL21439565 | 0.91 | CFD (0.42) | CFDBRD4CREBBPF11TPSB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |