Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 3/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21439052 | 0.87 | BRD4 (0.47) | BRD4CREBBPKDM4AGLSCCKBR | |
| SCHEMBL21438280 | 0.87 | BRD4 (0.47) | BRD4CREBBPKDM4AGLSCCKBR | |
| SCHEMBL30009981 | 0.87 | BRD4 (0.47) | BRD4CREBBPKDM4AGLSCCKBR | |
| SCHEMBL23616972 | 0.87 | BRD4 (0.47) | BRD4CREBBPKDM4AGLSCCKBR | |
| SCHEMBL21437507 | 0.86 | BRD4 (0.47) | BRD4CREBBPKDM4AGLSCCKBR | |
| SCHEMBL21455698 | 0.86 | BRD4 (0.47) | BRD4CREBBPKDM4AGLSCCKBR | |
| SCHEMBL29672928 | 0.86 | BRD4 (0.47) | BRD4CREBBPKDM4AGLSCCKBR | |
| SCHEMBL21455247 | 0.86 | CFD (0.47) | BRD4CREBBPGLSCCKBRHDAC1 | |
| SCHEMBL21437665 | 0.86 | BRD4 (0.46) | BRD4CREBBPKDM4AGLSCCKBR | |
| SCHEMBL29672922 | 0.86 | BRD4 (0.46) | BRD4CREBBPKDM4AGLSCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |