SCHEMBL23617138

SCHEMBL23617138

COc1cccc(CC=S)c1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.55
IDO1 P14902 2/20 0.55
AGXT P21549 2/20 0.55
CHRM2 P08172 4/20 0.51
CHRM1 P11229 3/20 0.51
CHRM3 P20309 3/20 0.51
CMA1 P23946 1/20 0.50
SIGMAR1 Q99720 2/20 0.49
MAOB P27338 2/20 0.49
AOC3 Q16853 1/20 0.49
LPO P22079 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8305017 0.84 TAAR1 (0.58) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL3503547 0.82 TAAR1 (0.56) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL248658 0.82 CHRM2 (0.57) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL7481915 0.81 TAAR1 (0.55) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL2091147 0.81 ALDH1A1 (0.60) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL28230126 0.81 TAAR1 (0.55) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL29382328 0.81 ALDH1A1 (0.60) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL6202449 0.81 TAAR1 (0.55) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL8465634 0.81 TAAR1 (0.55) TAAR1IDO1AGXTCHRM2CHRM1
SCHEMBL7746095 0.79 TAAR1 (0.53) TAAR1IDO1AGXTCHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
EP-3687506-B1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS BIOCRYST PHARM INC (US) 2021-07-07 EP disclosed